Computational prediction of lncRNA-mRNA interactions by integrating tissue specificity in human transcriptome
Abstract
Long noncoding RNAs (lncRNAs) play a key role in normal tissue differentiation and cancer development through their tissue-specific expression in the human transcriptome. Recent investigations of macromolecular interactions have shown that tissue-specific lncRNAs form base-pairing interactions with various mRNAs associated with tissue-differentiation, suggesting that tissue specificity is an important factor controlling human lncRNA-mRNA...
Paper Details
Title
Computational prediction of lncRNA-mRNA interactions by integrating tissue specificity in human transcriptome
Published Date
Jun 8, 2017
Journal
Volume
12
Issue
1
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