TGF-β 1 (Transforming Growth Factor-β 1 ) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity
Abstract
Background— TGF-β 1 (transforming growth factor-β 1 ) importantly contributes to cardiac fibrosis by controlling differentiation, migration, and collagen secretion of cardiac myofibroblasts. It is still elusive, however, to which extent TGF-β 1 alters the electrophysiological phenotype of myofibroblasts and cardiomyocytes and whether it affects proarrhythmic myofibroblast–cardiomyocyte crosstalk observed in vitro. Methods and Results—...
Paper Details
Title
TGF-β 1 (Transforming Growth Factor-β 1 ) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity
Published Date
May 1, 2017
Volume
10
Issue
5
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