MicroRNA-338 modulates cortical neuronal placement and polarity
Abstract
The precise spatial and temporal regulation of gene expression orchestrates the many intricate processes during brain development. In the present study we examined the role of the brain-enriched microRNA-338 (miR-338) during mouse cortical development. Reduction of miR-338 levels in the developing mouse cortex, using a sequence-specific miR-sponge, resulted in a loss of neuronal polarity in the cortical plate and significantly reduced the number...
Paper Details
Title
MicroRNA-338 modulates cortical neuronal placement and polarity
Published Date
Jun 15, 2017
Journal
Volume
14
Issue
7
Pages
905 - 913
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