Original paper
Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse
Abstract
Synapse development and neuronal activity represent fundamental processes for the establishment of cognitive function. Structural organization as well as signalling pathways from receptor stimulation to gene expression regulation are mediated by synaptic activity and misregulated in neurodevelopmental disorders such as autism spectrum disorder (ASD) and intellectual disability (ID). Deleterious mutations in the PTCHD1 (Patched domain containing...
Paper Details
Title
Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse
Published Date
Apr 18, 2017
Journal
Volume
23
Issue
5
Pages
1356 - 1367
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Notes
History