Original paper
The role of axonal Kv1 channels in CA3 pyramidal cell excitability
Abstract
Axonal ion channels control spike initiation and propagation along the axon and determine action potential waveform. We show here that functional suppression of axonal Kv1 channels with local puff of dendrotoxin (DTx), laser or mechanical axotomy significantly increased excitability measured in the cell body. Importantly, the functional effect of DTx puffing or axotomy was not limited to the axon initial segment but was also seen on axon...
Paper Details
Title
The role of axonal Kv1 channels in CA3 pyramidal cell excitability
Published Date
Mar 22, 2017
Journal
Volume
7
Issue
1
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Notes
History