Original paper
The Enrichment of HBV Immune-Escape Mutations during Nucleoside/Nucleotide Analogue Therapy
Abstract
Background Drug-resistant HBV mutants frequently arise during nucleoside/nucleotide analogue (NA) therapy, while the resistance mutations on polymerase also have consequent changes in the S protein. The enrichment of immune-escape mutations was negatively correlated with hepatitis B surface antigen (HBsAg) clearance under NA therapy. This study aims to characterize the variability of HBV polymerase and surface antigen in patients with...
Paper Details
Title
The Enrichment of HBV Immune-Escape Mutations during Nucleoside/Nucleotide Analogue Therapy
Published Date
Nov 1, 2016
Journal
Volume
22
Issue
8
Pages
717 - 720
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Notes
History