Review paper

Nod2: The intestinal gate keeper

Volume: 13, Issue: 3, Pages: e1006177 - e1006177
Published: Mar 2, 2017
Abstract
Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular pattern recognition receptor that senses bacterial peptidoglycan (PGN)-conserved motifs in cytosol and stimulates host immune response. The association of NOD2 mutations with a number of inflammatory pathologies, including Crohn disease (CD), Graft-versus-host disease (GVHD), and Blau syndrome, highlights its pivotal role in host-pathogen interactions and inflammatory...
Paper Details
Title
Nod2: The intestinal gate keeper
Published Date
Mar 2, 2017
Volume
13
Issue
3
Pages
e1006177 - e1006177
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