T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow
Abstract
Long-lived plasma cells (PCs) in the bone marrow (BM) are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs and regulatory T (Treg) cells, a population that contributes to immune privilege in the BM. The use of intravital imaging revealed that BM Treg cells display a distinct behavior characterized by...
Paper Details
Title
T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow
Published Date
Feb 1, 2017
Journal
Volume
18
Issue
8
Pages
1906 - 1916
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Notes
History