Toxicological Characterization of the Thermal Decomposition Products of Chemicals: a New Approach to an Old Problem

Different calorimetric techniques coupled with chemical analyses and ecotoxicological bioassay led to the proposal of suitable protocol for the definition of a KPI (Key Process Index) useful to rank a compound in respect to the toxicological profile of its thermal decomposition products. Fenitrothion was used as example and showed to decompose through a series of two main processes, the first being less severe than the second. It is demonstrated...