Building a lineage from single cells: genetic techniques for cell lineage tracking
Abstract
Lineage analyses of multicellular organisms provide key insights into developmental mechanisms and how these developmental trajectories go awry in diverse diseases. This Review discusses the features, technical challenges and latest opportunities of an evolving range of sophisticated genetic techniques for tracking cell lineages in organisms. These strategies include methods for prospective tracking using engineered genetic constructs, as well...
Paper Details
Title
Building a lineage from single cells: genetic techniques for cell lineage tracking
Published Date
Jan 23, 2017
Journal
Volume
18
Issue
4
Pages
230 - 244
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Notes
History