Original paper

Translation system engineering in Escherichia coli enhances non‐canonical amino acid incorporation into proteins

Volume: 114, Issue: 5, Pages: 1074 - 1086
Published: Feb 2, 2017
Abstract
The ability to site-specifically incorporate non-canonical amino acids (ncAAs) into proteins has made possible the study of protein structure and function in fundamentally new ways, as well as the bio synthesis of unnatural polymers. However, the task of site-specifically incorporating multiple ncAAs into proteins with high purity and yield continues to present a challenge. At the heart of this challenge lies the lower efficiency of engineered...
Paper Details
Title
Translation system engineering in Escherichia coli enhances non‐canonical amino acid incorporation into proteins
Published Date
Feb 2, 2017
Volume
114
Issue
5
Pages
1074 - 1086
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