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Association of 25-hydroxyvitamin D and parathyroid hormone with the metabolic syndrome in black South African women

Published on Apr 1, 2017in Applied Physiology, Nutrition, and Metabolism3.455
· DOI :10.1139/apnm-2016-0257
Olusola F. Sotunde2
Estimated H-index: 2
(NWU: North-West University),
Herculina S. Kruger22
Estimated H-index: 22
(NWU: North-West University)
+ 4 AuthorsMarlien Pieters16
Estimated H-index: 16
(NWU: North-West University)
Abstract
The relationship between 25 hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and metabolic traits appear to differ among ethnicities and may be influenced by obesity. The aim of the study was to examine the association of serum 25(OH)D or PTH with metabolic syndrome (MetS) while controlling for adiposity in black women. Using a cross-sectional study design, 209 urban black women aged ≥ 43 years from the North West Province, South Africa, were included. Multiple regression models were used to explore the relationship between 25(OH)D or PTH and body composition. To explore the association between 25(OH)D or PTH and MetS, a separate variable was created including at least 3 of the MetS criteria, but excluding elevated waist circumference as a diagnostic criterion in a logistic regression model. The majority of the women (69.9%) were overweight or obese and 65.5% of the women had excessive adiposity using the age-specific cut-off points for body fat percentage. All body composition variables were positiv...
  • References (42)
  • Citations (1)
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References42
Newest
#1Sandra N. Slagter (UMCG: University Medical Center Groningen)H-Index: 10
#2Jana V. van Vliet-Ostaptchouk (UMCG: University Medical Center Groningen)H-Index: 30
Last. Bruce H. R. Wolffenbuttel (UMCG: University Medical Center Groningen)H-Index: 63
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Introduction - The development of metabolic syndrome (MetS) is influenced by environmental factors such as smoking and alcohol consumption. We determined the combined effects of smoking and alcohol on MetS and its individual components. Methods - 64,046 participants aged 18–80 years from the LifeLines Cohort study were categorized into three body mass index (BMI) classes (BMI1 drink/day) and tobacco showed higher triglycerides levels. Up to 2 drinks/day was associated with a smaller waist circum...
39 CitationsSource
#1Jaya A. George (National Health Laboratory Service)H-Index: 4
#2Shane A. Norris (University of the Witwatersrand)H-Index: 15
Last. Nigel J. Crowther (National Health Laboratory Service)H-Index: 28
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Introduction: Though inconsistent, a number of studies have shown an association between vitamin D (25(OH)D) status, parathyroid hormone (PTH) and the metabolic syndrome (Met S). These have largely been carried out in Caucasians or black subjects living in high income countries. There no data on the relationship of 25(OH)D and PTH status with Met S in populations resident in Africa. The aims of this study were to evaluate if there was an association of 25(OH)D or PTH with Met S in non-Caucasian ...
27 CitationsSource
#1Xiao Yin (SDU: Shandong University)H-Index: 1
#2Qiang Sun (SDU: Shandong University)H-Index: 55
Last. Shaolian Wang (SDU: Shandong University)H-Index: 1
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Background Vitamin D deficiency is associated with a variety of chronic metabolic diseases. Limited evidence regarding vitamin D deficiency exists within the Chinese population. The present study aims to examine the association between serum vitamin D concentrations and cardiometabolic risk factors in the young and middle-aged, urban Chinese population
36 CitationsSource
#1Alexandra Jungert (University of Giessen)H-Index: 6
#2Heinz J RothH-Index: 3
Last. Monika Neuhäuser-Berthold (University of Giessen)H-Index: 16
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Background: Emerging evidence indicates that there is an association between vitamin D and obesity. The aim of this study was to investigate whether the level of serum 25-hydroxyvitamin D3 [25(OH)D3] in the elderly is influenced by parameters of anthropometry and body composition independent of potential confounding lifestyle factors and the level of serum intact parathyroid hormone (iPTH). Methods: Cross-sectional data of 131 independently living participants (90 women, 41 men; aged 66–96 years...
26 CitationsSource
#1Moonseong HeoH-Index: 57
#2Myles S. Faith (UNC: University of North Carolina at Chapel Hill)H-Index: 24
Last. Steven B. Heymsfield (Pennington Biomedical Research Center)H-Index: 111
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Background: To date, there is no consensus regarding adult cutoffs of percentage of body fat or estimated cutoffs on the basis of nationally representative samples with rigorous body-composition measurements. Objective: We developed cutoffs of percentage of body fat on the basis of the relation between dual-energy x-ray absorptiometry– measured fat mass and BMI (in kg/m 2 ) stratified by sex, age, and race-ethnicity by using 1999–2004 NHANES data. Design: A simple regression (percentage of body ...
79 CitationsSource
#1Marlena C. Kruger (Massey University)H-Index: 27
#2Iolanthé M. Kruger (NWU: North-West University)H-Index: 7
Last. Annamarie Kruger (NWU: North-West University)H-Index: 24
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Abstract Globally, rural to urban migration is accompanied by changes in dietary patterns and lifestyle that have serious health implications, including development of low bone mass. We hypothesized that serum 25 (OH) vitamin D3 (25[OH]D3) levels will be lower, bone turnover higher, and nutrition inadequate in urban postmenopausal black women, increasing risk for low bone mass. We aimed to assess the prevalence of risk factors for low bone mass in 1261 black women from rural and urban areas in t...
34 CitationsSource
#1Michael F. Holick (BU: Boston University)H-Index: 124
#2Neil Binkley (UW: University of Wisconsin-Madison)H-Index: 59
Last. Connie M. Weaver (Purdue University)H-Index: 64
view all 8 authors...
Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. Participants: The Task Force was composed of a Chair, six additional experts, and a methodologist. The Task Force received no corporate funding or remuneration. Consensus Process: Consensus was guided by systematic reviews of evidence and discussions during several conference calls and e-mai...
4,155 CitationsSource
#1Hester H Vorster (University of Southampton)H-Index: 35
#2Annamarie Kruger (NWU: North-West University)H-Index: 24
Last. Barrie Margetts (NWU: North-West University)H-Index: 48
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The objective of this narrative review is to examine the nutrition transition and its consequences when populations in Africa modernize as a result of socio-economic development, urbanization, and acculturation. The focus is on the changes in dietary patterns and nutrient intakes during the nutrition transition, the determinants and consequences of these changes as well as possible new approaches in public health nutrition policies, interventions and research needed to steer the nutrition transi...
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#1Ayesha A. MotalaH-Index: 24
Last. Mahomed A.K. OmarH-Index: 17
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OBJECTIVE To determine the prevalence of metabolic syndrome and to define optimal ethnic-specific waist-circumference cutoff points in a rural South African black community. RESEARCH DESIGN AND METHODS This was a cross-sectional survey conducted by random-cluster sampling of adults aged >15 years. Participants had demographic, anthropometric, and biochemical measurements taken, including a 75-g oral glucose tolerance test. Metabolic syndrome was defined using the 2009 Joint Interim Statement (JI...
96 CitationsSource
#1Felix K. Assah (Medical Research Council)H-Index: 15
#2Ulf Ekelund (Medical Research Council)H-Index: 86
Last. Nicholas J. Wareham (Medical Research Council)H-Index: 169
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Background: The increasing burden of non-communicable diseases in sub-Saharan Africa warrants rigorous studies of contributing lifestyle factors. Combined heart rate and movement monitoring make it possible to objectively measure physical activity in free-living individuals. We examined the validity of a combined heart rate and motion sensor in estimating physical activity energy expenditure (PAEE) in free-living adults in rural and urban Cameroon compared to doubly-labelled water (DLW) as crite...
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#1Hester Jaspers Faijer-Westerink (PHRI: Public Health Research Institute)
#2Andre Pascal Kengne (South African Medical Research Council)H-Index: 51
Last. Charles Agyemang (PHRI: Public Health Research Institute)H-Index: 42
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Abstract Background and Aims There are rising levels of cardiovascular diseases (CVDs) and diabetes in Sub-Saharan Africa (SSA). Metabolic syndrome (MS) is a precursor of these conditions, but the data on the prevalence of MS in SSA are fragmented. We conducted a systematic review and meta-analysis to estimate the prevalence of MS in SSA and determine the population groups that are most at risk. Methods and Results We systematically searched PubMed, EMBASE and African Journals Online for all pub...
Source
The parameters of phosphorus–calcium metabolism at different levels of 25 (OH)D in young people have been studied. The studied population included 48 young men and 126 young women aged 18 to 20 years. Normal values of vitamin D were found in 40 subjects (23%); the blood level of 25-OH vitamin D was shown to be 20–30 ng/mL in 59 subjects (34%), 10–19 ng/mL in 56 subjects (32%), and <10 ng/mL in 19 subjects (11%). The calcium level proved to be associated with the rate of vitamin D deficiency. The...
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#1Hattie H. WrightH-Index: 7
#2Marlena C. KrugerH-Index: 27
Last. Herculina S. KrugerH-Index: 22
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This prospective study investigated the association between nutrient intake, dietary patterns, and changes in bone turnover and bone mineral density (BMD) in postmenopausal urban black South African women over two years. These women (n = 144) underwent BMD measurements at the distal radius, lumbar spine, femoral neck (FN), as well as a biochemical analysis which included the parathyroid hormone (PTH), 25-hydroxyvitamin D, C-Telopeptide of type I collagen (CTX-1) in 2010 and 2012. Their dietary i...
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