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Marlien Pieters
North-West University
EndocrinologyFibrinogenFibrinDiabetes mellitusMedicine
71Publications
17H-index
1,290Citations
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Publications 70
Newest
#1Cristian Ricci (NWU: North-West University)H-Index: 4
#2Heinz Freisling (IARC: International Agency for Research on Cancer)H-Index: 29
Last. Marlien Pieters (NWU: North-West University)H-Index: 17
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Summary Background and aims Cancer is the second most common chronic disease and cause of death in the United States. Our aim was to evaluate the associations of sedentary behavior and nutrient intakes with total and cancer-specific mortality among US cancer survivors. Methods Data from 2,371 cancer survivors collected by the US National Health and Nutrition Examination Survey between 1999 and 2014 were linked to the US mortality registry. Multivariable adjusted Cox proportional hazard models we...
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#1Ali DaraeiH-Index: 3
Last. Martin GutholdH-Index: 29
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#1Cristian Ricci (NWU: North-West University)H-Index: 4
#2Aletta Elizabeth Schutte (NWU: North-West University)
Last. Marlien Pieters (NWU: North-West University)H-Index: 17
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BACKGROUND: Excessive alcohol use is the third leading cause of mortality in the United States, where alcohol use consistently increased over the last decades. This trend is currently maintained, despite regulatory policies aimed to counteract it. While the increased health risks resulting from alcohol use are evident, some open questions regarding alcohol use and its consequences in the US population remain. OBJECTIVES: The current work aims to evaluate the relation between alcohol consumption ...
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#1H. Toinét Cronjé (NWU: North-West University)H-Index: 2
Last. Marlien Pieters (NWU: North-West University)H-Index: 17
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BACKGROUND: DNA methylation is associated with non-communicable diseases (NCDs) and related traits. Methylation data on continental African ancestries are currently scarce, even though there are known genetic and epigenetic differences between ancestral groups and a high burden of NCDs in Africans. Furthermore, the degree to which current literature can be extrapolated to the understudied African populations, who have limited resources to conduct independent large-scale analysis, is not yet know...
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#1Marlien Pieters (NWU: North-West University)H-Index: 17
#2Martin Guthold (Wake Forest University)H-Index: 29
Last. Zelda de Lange (NWU: North-West University)H-Index: 6
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Turbidimetry is used to characterize fibrin clot properties. In purified systems, maximum absorbance (MA) directly relates to fibrin fiber cross-sectional area. However, in plasma samples there are discrepancies in the relationships between MA and fibrinogen concentration, fiber diameter, other clot properties, and cardiovascular disease outcomes, which complicate data interpretation. This study aims to advance understanding of MA of plasma clots through testing how well it relates to fundamenta...
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#1Adriaan JacobsH-Index: 1
#2Aletta E. Schutte (NWU: North-West University)H-Index: 47
Last. Marlien PietersH-Index: 17
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Objectives:Plasminogen activator inhibitor-1 (PAI-1) has consistently shown positive associations with blood pressure (BP). Whether elevations in PAI-1 levels precede or result from raised BP is still under debate and data on prospective studies are limited. Hence, we investigated the prospective as
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#1Alice Achieng Ojwang (NWU: North-West University)H-Index: 1
#2Herculina S. Kruger (NWU: North-West University)H-Index: 23
Last. Cornelius M. Smuts (NWU: North-West University)H-Index: 14
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BACKGROUND: Diets rich in n-6 polyunsaturated fatty acids (PUFAs) and saturated fatty acids (SFA) have been associated with increased risk of obesity and the metabolic syndrome (MetS), but the evidence is inconsistent, whereas diets high in n-3 long-chain (LC) -PUFAs are associated with lower risk. There is limited information about the association of plasma phospholipid fatty acids (FAs) with obesity and the MetS among black South Africans. OBJECTIVE: To investigate the association of dietary F...
2 CitationsSource
#1Z. de Lange (NWU: North-West University)H-Index: 3
#2B. Kahler (NWU: North-West University)
Last. Marlien Pieters (NWU: North-West University)H-Index: 17
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Abstract Evidence regarding the relationship of plasma clot properties with fatty acids is contradictory, owing to different experimental protocols employed. The relationship of fibrinogen and plasma fibrin clot properties with plasma phospholipid fatty acids were cross-sectionally investigated in a population-based setting in 900 individuals. Composite saturated fatty acids (driven by stearic acid) and composite n-3 and n-6 polyunsaturated fatty acids (driven by docosahexaenoic and arachidonic ...
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#1Marlien Pieters (NWU: North-West University)H-Index: 17
#2Alisa S. Wolberg (UNC: University of North Carolina at Chapel Hill)H-Index: 33
: Since its discovery over 350 years ago, studies of fibrinogen have revealed remarkable characteristics. Its complex structure as a large (340 kDa) hexameric homodimer supports complex roles in hemostasis and homeostasis. Fibrinogen synthesis is regulated at the transcriptional and translational levels, undergoing both constitutive (basal) secretion from liver, and inducible upregulation in response to inflammatory events. In addition, alternative splicing yields fibrinogen variants with unique...
4 CitationsSource
#1Aletta E. Schutte (South African Medical Research Council)H-Index: 47
#2Philimon Gona (University of Massachusetts Boston)
Last. Hugo W. Huisman (South African Medical Research Council)H-Index: 22
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BackgroundGlobally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective ...
3 CitationsSource
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