Marlien Pieters
North-West University
Publications 64
#1Marlien Pieters (NWU: North-West University)H-Index: 14
#2Alisa S. Wolberg (UNC: University of North Carolina at Chapel Hill)H-Index: 29
#1Z. de Lange (NWU: North-West University)H-Index: 2
#2B. Kahler (NWU: North-West University)
Last.Marlien Pieters (NWU: North-West University)H-Index: 14
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Abstract Evidence regarding the relationship of plasma clot properties with fatty acids is contradictory, owing to different experimental protocols employed. The relationship of fibrinogen and plasma fibrin clot properties with plasma phospholipid fatty acids were cross-sectionally investigated in a population-based setting in 900 individuals. Composite saturated fatty acids (driven by stearic acid) and composite n-3 and n-6 polyunsaturated fatty acids (driven by docosahexaenoic and arachidonic ...
#1Aletta E. Schutte (South African Medical Research Council)H-Index: 41
#2Philimon Gona (University of Massachusetts Boston)H-Index: 54
Last.Wayne Smith (South African Medical Research Council)H-Index: 11
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BackgroundGlobally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective ...
#1H. Toinét Cronjé (NWU: North-West University)H-Index: 1
#2Cornelie Nienaber-Rousseau (NWU: North-West University)H-Index: 4
Last.Marlien Pieters (NWU: North-West University)H-Index: 14
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Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by the high linkage disequilibrium (LD) reported in the European fibrinogen gene locus. This study investigated two novel and 12 known fibrinogen SNPs of potential functional relevance, in 2010 Tswana in...
#1Mahshid Dehghan (Population Health Research Institute)H-Index: 22
#2Andrew Mente (McMaster University)H-Index: 30
Last.Anders H. Rosengren (University of Gothenburg)H-Index: 84
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Summary Background The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. Methods The Prospective Urban Rural Epidemiology (PURE) study is a large, epidemiological cohort study of individuals aged 35–70 years (enrolled between Jan 1, 2003, and March 31, 2013) in 18 countries with a median fo...
#1Victoria Miller (Population Health Research Institute)H-Index: 2
#2Andrew Mente (Population Health Research Institute)H-Index: 30
Last.Scott A. Lear (SFU: Simon Fraser University)H-Index: 39
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Summary Background The association between intake of fruits, vegetables, and legumes with cardiovascular disease and deaths has been investigated extensively in Europe, the USA, Japan, and China, but little or no data are available from the Middle East, South America, Africa, or south Asia. Methods We did a prospective cohort study (Prospective Urban Rural Epidemiology [PURE] in 135 335 individuals aged 35 to 70 years without cardiovascular disease from 613 communities in 18 low-income, middle-i...