Original paper
CRISPR-Cas9 for the genome engineering of cyanobacteria and succinate production
Abstract
Cyanobacteria hold promise as a cell factory for producing biofuels and bio-derived chemicals, but genome engineering of cyanobacteria such as Synechococcus elongatus PCC 7942 poses challenges because of their oligoploidy nature and long-term instability of the introduced gene. CRISPR-Cas9 is a newly developed RNA-guided genome editing system, yet its application for cyanobacteria engineering has yet to be reported. Here we demonstrated that...
Paper Details
Title
CRISPR-Cas9 for the genome engineering of cyanobacteria and succinate production
Published Date
Nov 1, 2016
Journal
Volume
38
Pages
293 - 302
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Notes
History