Associations between microRNA binding site SNPs in FGFs and FGFRs and the risk of non-syndromic orofacial cleft
Abstract
We hypothesized that microRNA binding site single nucleotide polymorphisms (SNPs) in fibroblast growth factors (FGFs) and their receptor genes (FGFRs) may affect microRNA and mRNA interactions and are thereby associated with susceptibility of non-syndromic orofacial cleft (NSOC). Ten SNPs among the FGF and FGFR genes were selected and their associations with NSOC susceptibility were investigated in a case-control study of 602 patients with NSOC...
Paper Details
Title
Associations between microRNA binding site SNPs in FGFs and FGFRs and the risk of non-syndromic orofacial cleft
Published Date
Aug 11, 2016
Journal
Volume
6
Issue
1
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