Original paper

Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism

Volume: 7, Issue: 9, Pages: e2348 - e2348
Published: Sep 1, 2016
Abstract
Neutrophils play an indispensable role in killing of invading pathogens by enhancing reactive oxygen species (ROS) and NO generation, and subsequently undergoing apoptosis. Unlike ROS/NOX2, role of NO/NOS still remains undefined in the apoptosis of neutrophils (PMNs) and the present study attempts to decipher the importance of NO/NOS in the neutrophil apoptosis. Prolonged treatment of human PMNs or mice bone marrow derived neutrophils (BMDN)...
Paper Details
Title
Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism
Published Date
Sep 1, 2016
Volume
7
Issue
9
Pages
e2348 - e2348
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