Review paper
From Krebs to clinic: glutamine metabolism to cancer therapy
Abstract
The resurgence of research into cancer metabolism has recently broadened interests beyond glucose and the Warburg effect to other nutrients, including glutamine. Because oncogenic alterations of metabolism render cancer cells addicted to nutrients, pathways involved in glycolysis or glutaminolysis could be exploited for therapeutic purposes. In this Review, we provide an updated overview of glutamine metabolism and its involvement in...
Paper Details
Title
From Krebs to clinic: glutamine metabolism to cancer therapy
Published Date
Jul 29, 2016
Journal
Volume
16
Issue
10
Pages
619 - 634
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