Regulation of MerTK, GPNMB, and VSIG4 on mouse macrophages
Volume: 196, Issue: 1_Supplement, Pages: 201.6 - 201.6
Published: May 1, 2016
Abstract
We have developed flow cytometry antibodies against three molecules expressed on tissue-resident mouse macrophages: MerTK, GPNMB (aka Osteoactivin, DC-HIL), and VSIG4 (aka CRIg). MerTK, a receptor tyrosine kinase, plays a crucial role in the clearance of apoptotic cells, as well as in the regulation of cytokine secretion and survival. MerTK is highly expressed by splenic red pulp macrophages, which aid in the clearance of apoptotic cells in the...
Paper Details
Title
Regulation of MerTK, GPNMB, and VSIG4 on mouse macrophages
Published Date
May 1, 2016
Journal
Volume
196
Issue
1_Supplement
Pages
201.6 - 201.6
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