Original paper
Highly bioavailable silibinin nanoparticles inhibit HCV infection
Abstract
Objective
Silibinin is a flavonolignan that is well established for its robust antiviral activity against HCV infection and has undergone several clinical trials for the management of hepatitis C. Despite its potency, silibinin suffers from poor solubility and bioavailability, restricting its clinical use. To overcome this limitation, we developed highly bioavailable silibinin nanoparticles (SB-NPs) and evaluated their efficiency...Paper Details
Title
Highly bioavailable silibinin nanoparticles inhibit HCV infection
Published Date
Jul 19, 2016
Journal
Volume
66
Issue
10
Pages
1853 - 1861
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Notes
History