Original paper

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Volume: 119, Issue: 5, Pages: 652 - 665
Published: Aug 19, 2016
Abstract
Rationale: The diabetes mellitus drug metformin is under investigation in cardiovascular disease, but the molecular mechanisms underlying possible benefits are poorly understood. Objective: Here, we have studied anti-inflammatory effects of the drug and their relationship to antihyperglycemic properties. Methods and Results: In primary hepatocytes from healthy animals, metformin and the IKKβ (inhibitor of kappa B kinase) inhibitor BI605906 both...
Paper Details
Title
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Published Date
Aug 19, 2016
Volume
119
Issue
5
Pages
652 - 665
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