Original paper
Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation
Volume: 478, Issue: 1, Pages: 398 - 402
Published: Sep 1, 2016
Abstract
Replication initiator 1 (Repin1) is a zinc finger protein playing a role in insulin sensitivity, body fat mass and lipid metabolism by regulating the expression key genes of glucose and lipid metabolism. Here, we tested the hypothesis that introgression of a Repin1 deletion into db/db mice improves glucose metabolism in vivo. We generated a whole body Repin1 deficient db/db double knockout mouse (Rep1−/−x db/db) and systematically characterized...
Paper Details
Title
Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation
Published Date
Sep 1, 2016
Volume
478
Issue
1
Pages
398 - 402
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