Original paper
Characterization of the targeting signal in mitochondrial β-barrel proteins
Abstract
Mitochondrial β-barrel proteins are synthesized on cytosolic ribosomes and must be specifically targeted to the organelle before their integration into the mitochondrial outer membrane. The signal that assures such precise targeting and its recognition by the organelle remained obscure. In the present study we show that a specialized β-hairpin motif is this long searched for signal. We demonstrate that a synthetic β-hairpin peptide competes with...
Paper Details
Title
Characterization of the targeting signal in mitochondrial β-barrel proteins
Published Date
Jun 27, 2016
Journal
Volume
7
Issue
1
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Notes
History