Original paper

Crosstalk between mismatch repair and base excision repair in human gastric cancer

Volume: 8, Issue: 49, Pages: 84827 - 84840
Published: Jun 20, 2016
Abstract
DNA repair gene expression in a set of gastric cancers suggested an inverse association between the expression of the mismatch repair (MMR) gene MLH1 and that of the base excision repair (BER) gene DNA polymerase β (Polβ). To gain insight into possible crosstalk of these two repair pathways in cancer, we analysed human gastric adenocarcinoma AGS cells over-expressing Polβ or Polβ active site mutants, alone or in combination with MLH1 silencing....
Paper Details
Title
Crosstalk between mismatch repair and base excision repair in human gastric cancer
Published Date
Jun 20, 2016
Journal
Volume
8
Issue
49
Pages
84827 - 84840
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