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Eugenia Dogliotti
Istituto Superiore di Sanità
166Publications
40H-index
5,334Citations
Publications 166
Newest
Published on Oct 10, 2018in Stem Cells International3.90
Mahara Valverde19
Estimated H-index: 19
(UNAM: National Autonomous University of Mexico),
Jonathan Lozano-Salgado (UNAM: National Autonomous University of Mexico)+ 3 AuthorsEugenia Dogliotti40
Estimated H-index: 40
(ISS: Istituto Superiore di Sanità)
Human adipose-derived mesenchymal stem cells (hADMSCs) are recognized as a potential tool in cell tissue therapy because of their capacity to proliferate and differentiate in vitro. Several studies have addressed their use in regenerative medicine; however, little is known regarding their response to DNA damage and in particular to the reactive oxygen species (ROS) that are present in the microenvironment of implantation. In this study, we used the ROS-inducing agent hydrogen peroxide to explore...
Published on Feb 19, 2018in Oncotarget
Barbara Pascucci16
Estimated H-index: 16
,
Alessandra Fragale14
Estimated H-index: 14
+ 6 AuthorsMariarosaria D’Errico8
Estimated H-index: 8
// Barbara Pascucci 1, 3 , Alessandra Fragale 2 , Veronica Marabitti 3 , Giuseppe Leuzzi 3, 4 , Angelo Salvatore Calcagnile 3 , Eleonora Parlanti 3 , Annapaola Franchitto 3 , Eugenia Dogliotti 3 and Mariarosaria D’Errico 3 1 Institute of Cristallography, Consiglio Nazionale delle Ricerche, Roma, Italy 2 Section of Tumor Immunology, Department of Oncology and Molecular Medicine, Istituto Superiore di Sanita, Roma, Italy 3 Section of Mechanisms, Biomarkers and Models, Department of Environment and...
Published on Nov 28, 2017in Oncotarget
Barbara Pascucci16
Estimated H-index: 16
(ISS: Istituto Superiore di Sanità),
Mariarosaria D’Errico8
Estimated H-index: 8
(ISS: Istituto Superiore di Sanità)
+ 14 AuthorsSara Baccarini7
Estimated H-index: 7
(ISS: Istituto Superiore di Sanità)
The ERCC8/CSA gene encodes a WD-40 repeat protein (CSA) that is part of a E3-ubiquitin ligase/COP9 signalosome complex. When mutated, CSA causes the Cockayne Syndrome group A (CS-A), a rare recessive progeroid disorder characterized by sun sensitivity and neurodevelopmental abnormalities. CS-A cells features include ROS hyperproduction, accumulation of oxidative genome damage, mitochondrial dysfunction and increased apoptosis that may contribute to the neurodegenerative process. In this study, w...
Published on Oct 17, 2017in Oncotarget
Valeria Simonelli7
Estimated H-index: 7
(ISS: Istituto Superiore di Sanità),
Giuseppe Leuzzi5
Estimated H-index: 5
(ISS: Istituto Superiore di Sanità)
+ 12 AuthorsBarbara Pascucci16
Estimated H-index: 16
// Valeria Simonelli 1, * , Giuseppe Leuzzi 1, * , Giorgia Basile 1, * , Mariarosaria D’Errico 1 , Paola Fortini 1 , Annapaola Franchitto 1 , Valentina Viti 2 , Ashley R. Brown 3 , Eleonora Parlanti 1 , Barbara Pascucci 4 , Domenico Palli 5 , Alessandro Giuliani 1 , Fabio Palombo 6 , Robert W. Sobol 3, 7, 8 , Eugenia Dogliotti 1 1 Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Rome, Italy 2 Istituto di Ricerche Biologia Molecolare P. Angeletti (IRBM), Pomezia (Ro...
Published on Jun 1, 2017in Free Radical Biology and Medicine5.66
Mariarosaria D’Errico8
Estimated H-index: 8
(ISS: Istituto Superiore di Sanità),
Eleonora Parlanti14
Estimated H-index: 14
(ISS: Istituto Superiore di Sanità)
+ 4 AuthorsEugenia Dogliotti40
Estimated H-index: 40
(ISS: Istituto Superiore di Sanità)
Abstract Oxidative stress is associated with a growing number of diseases that span from cancer to neurodegeneration. Most oxidatively induced DNA base lesions are repaired by the base excision repair (BER) pathway which involves the action of various DNA glycosylases. There are numerous genome wide studies attempting to associate single-nucleotide polymorphisms (SNPs) with predispositions to various types of disease; often, these common variants do not have significant alterations in their bioc...
Published on Nov 1, 2016in EFSA Journal
Helle Katrine Knutsen21
Estimated H-index: 21
,
Alexander J49
Estimated H-index: 49
+ 27 AuthorsChrister Hogstrand44
Estimated H-index: 44
Erucic acid is the trivial name of the fatty acid cis-13-docosenoic acid and occurs at high concentrations mainly in the seeds of species of the Brassicaceae (e.g. rape seed or mustard seed). The European Commission requested EFSA to deliver a scientific opinion on the risks for animal and human health related to the presence of erucic acid in feed and food. For most humans, the main contributor to dietary exposure to erucic acid was the food group ‘Fine bakery wares’. In ‘Infants’, ‘Food for in...
Published on Sep 1, 2016in Toxicology Letters3.50
Eugenia Dogliotti40
Estimated H-index: 40
(ISS: Istituto Superiore di Sanità)
Published on Aug 1, 2016in Free Radical Biology and Medicine5.66
Emanuela Medda20
Estimated H-index: 20
(ISS: Istituto Superiore di Sanità),
Anna Minoprio11
Estimated H-index: 11
(ISS: Istituto Superiore di Sanità)
+ 11 AuthorsLuisa Minghetti47
Estimated H-index: 47
(ISS: Istituto Superiore di Sanità)
Abstract Inefficient response to oxidative stress has been associated with ageing and health risk. Metals are known to inhibit DNA repair and may modify the antioxidant response. How genetic variability and lifestyle factors modulate the response to oxidative stress is poorly explored. Our study aims to disentangle the contribution of genetics and environmental exposures to oxidative stress response using data from twin pairs. The non-enzymatic antioxidant capacity (NEAC), the repair capacity of...
Published on Jun 16, 2016in Frontiers in Physiology3.20
Paola Fortini21
Estimated H-index: 21
(ISS: Istituto Superiore di Sanità),
Egidio Iorio19
Estimated H-index: 19
(ISS: Istituto Superiore di Sanità)
+ 1 AuthorsCiro Isidoro33
Estimated H-index: 33
Autophagy undergoes a fine tuning during tissue differentiation and organ remodelling in order to meet the dynamic changes in the metabolic needs. While the involvement of autophagy in the homeostasis of mature muscle tissues has been intensively studied, no study has so far addressed the regulation of autophagy in relation to the metabolic state during the myogenic differentiation. In our recently published study (Fortini et al., Cell Death Disease. 7, e2168. doi: 10.1038/cddis.2016.50) we inve...
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