The second decade of 3C technologies: detailed insights into nuclear organization
Abstract
The relevance of three-dimensional (3D) genome organization for transcriptional regulation and thereby for cellular fate at large is now widely accepted. Our understanding of the fascinating architecture underlying this function is based on microscopy studies as well as the chromosome conformation capture (3C) methods, which entered the stage at the beginning of the millennium. The first decade of 3C methods rendered unprecedented insights into...
Paper Details
Title
The second decade of 3C technologies: detailed insights into nuclear organization
Published Date
Jun 15, 2016
Journal
Volume
30
Issue
12
Pages
1357 - 1382
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