Original paper
Biphasic effects of hyposmotic challenge on excitation-contraction coupling in rat ventricular myocytes
Volume: 279, Issue: 4, Pages: H1963 - H1971
Published: Oct 1, 2000
Abstract
The effects of short (1 min) and long (7-10 min) exposure to hyposmotic solution on excitation-contraction coupling in rat ventricular myocytes were studied. After short exposure, the action potential duration at 90% repolarization (APD(90)), the intracellular Ca(2+) concentration ([Ca(2+)](i)) transient amplitude, and contraction increased, whereas the L-type Ca(2+) current (I(Ca, L)) amplitude decreased. Fractional sarcoplasmic reticulum (SR)...
Paper Details
Title
Biphasic effects of hyposmotic challenge on excitation-contraction coupling in rat ventricular myocytes
Published Date
Oct 1, 2000
Volume
279
Issue
4
Pages
H1963 - H1971
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Notes
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