Multicenter, Prospective Trial of Selective Drain Management for Pancreatoduodenectomy Using Risk Stratification

This multicenter study sought to prospectively evaluate a drain management protocol for pancreatoduodenectomy (PD).Recent evidence suggests value for both selective drain placement and early drain removal for PD. Both strategies have been associated with reduced rates of clinically relevant pancreatic fistula (CR-POPF)-the most common and morbid complication after PD.The protocol was applied to 260 consecutive PDs performed at two institutions...