Original paper

Senescence Can Be BETter without the SASP?

Volume: 6, Issue: 6, Pages: 576 - 578
Published: Jun 1, 2016
Abstract
Summary: Global remodeling of the chromatin landscape occurs during senescence, although its functional consequence is still unclear. In this issue, Tasdemir and colleagues show that the epigenetic regulator BRD4 is required for expression of the proinflammatory senescence-associated secretory phenotype and immune clearance of senescent cells in vitro and in vivo. Their results could be useful in the design of novel therapies to treat...
Paper Details
Title
Senescence Can Be BETter without the SASP?
Published Date
Jun 1, 2016
Volume
6
Issue
6
Pages
576 - 578
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