Deferoxamine alleviates liver fibrosis induced by CCl4 in rats

Volume: 43, Issue: 8, Pages: 760 - 768
Published: Jul 4, 2016
Abstract
Several chronic liver diseases can lead to the occurrence of hepatic fibrosis through the accumulation of iron, which causes induction of oxidative stress and consequently activation of fibrogenesis. The present study was designed to investigate the potential antifibrotic and anti-oxidant effects of deferoxamine (DFO), a well-known iron chelator in an experimental rat model of liver injury using carbon tetrachloride (CCl4 ). First, the potential...
Paper Details
Title
Deferoxamine alleviates liver fibrosis induced by CCl4 in rats
Published Date
Jul 4, 2016
Volume
43
Issue
8
Pages
760 - 768
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