Portal vein thrombosis in cirrhosis is not associated with intestinal barrier disruption or increased platelet aggregability

Portal vein thrombosis (PVT) is a common complication of cirrhosis, but its pathogenesis is unclear. We tested the hypotheses that PVT is the result of platelet hyperactivity or intestinal barrier disruption. This study included 49 patients with cirrhosis (15 females) of mixed etiology. Based on spiral computed-tomography, the patients were divided into two groups: with PVT (n = 16) and without PVT (n = 33). Serum biomarkers of intestinal...