SOX9 and the many facets of its regulation in the chondrocyte lineage
Abstract
SOX9 is a pivotal transcription factor in developing and adult cartilage. Its gene is expressed from the multipotent skeletal progenitor stage and is active throughout chondrocyte differentiation. While it is repressed in hypertrophic chondrocytes in cartilage growth plates, it remains expressed throughout life in permanent chondrocytes of healthy articular cartilage. SOX9 is required for chondrogenesis: it secures chondrocyte lineage...
Paper Details
Title
SOX9 and the many facets of its regulation in the chondrocyte lineage
Published Date
Apr 29, 2016
Journal
Volume
58
Issue
1
Pages
2 - 14
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Notes
History