Advanced MRI and staging of multiple sclerosis lesions

MRI-based visualization of demyelinated CNS lesions is pivotal to the diagnosis and monitoring of multiple sclerosis (MS). The authors describe how advanced multimodal neuroimaging techniques are providing valuable insights into lesion structure and blood–brain barrier dynamics, thereby narrowing the gap between the macroscopic view of the radiologist and the microscopic view of the pathologist. The findings in humans are compared with data from...