Infrared-based detection of an osteoarthritis biomarker signature in the serum of rabbits with induced osteoarthritis

Purpose: Earlier and economic screening for the diagnosis and monitoring of osteoarthritis (OA) is required to allow timely intervention with preventive therapy to arrest or reverse structural degradation, and to minimize the disabling effects of OA. Biomarkers have gained widespread acceptance as tools for the characterization of OA and clinical trial responses, but progress in their use as screening tools in susceptible populations is limited....