Plasma Volume and Flight Duration Effects on Post-Spaceflight Soluble Adhesion Molecules

We examined the effects of plasma volume (PV) changes and flight duration on circulating soluble adhesion markers (sP-selection, sE-selection, and sICAM-1).Study participants were 22 astronauts (2 women). Missions ranged from 5 to 16 d. Astronauts were split into two groups: those who spent less than 8 d in space and those who spent more than 8 d in space. Soluble adhesion markers and PV were assessed 10 d prelaunch, immediately after landing,...