Clinical Management of Ebola Virus Disease in the United States and Europe

Published on Feb 18, 2016in The New England Journal of Medicine70.67
· DOI :10.1056/NEJMoa1504874
Timothy M. Uyeki71
Estimated H-index: 71
(CDC: Centers for Disease Control and Prevention),
Aneesh K. Mehta27
Estimated H-index: 27
(Emory University)
+ 14 AuthorsJulie Gutman17
Estimated H-index: 17
(CDC: Centers for Disease Control and Prevention)
BackgroundAvailable data on the characteristics of patients with Ebola virus disease (EVD) and clinical management of EVD in settings outside West Africa, as well as the complications observed in those patients, are limited. MethodsWe reviewed available clinical, laboratory, and virologic data from all patients with laboratory-confirmed Ebola virus infection who received care in U.S. and European hospitals from August 2014 through December 2015. ResultsA total of 27 patients (median age, 36 years [range, 25 to 75]) with EVD received care; 19 patients (70%) were male, 9 of 26 patients (35%) had coexisting conditions, and 22 (81%) were health care personnel. Of the 27 patients, 24 (89%) were medically evacuated from West Africa or were exposed to and infected with Ebola virus in West Africa and had onset of illness and laboratory confirmation of Ebola virus infection in Europe or the United States, and 3 (11%) acquired EVD in the United States or Europe. At the onset of illness, the most common signs and sy...
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