AB0578 Mepolizumab in the Treatment of Eosinophilic Granulomatosis with Polyangitis

Background

A double-blind, randomised, placebo-controlled, 60-week study of mepolizumab (300 mg every 4 weeks) in eosinophilic granulomatosis with polyangiitis (EGPA) is being sponsored by GlaxoSmithKline in collaboration with the National Institute of Allergy and Infectious Diseases (NIH) in the US. It is critical to ensure definition of the appropriate EPGA diagnostic criteria and study outcomes for this global study....