IgG4 Syndrome Presenting as Leptomeningitis in a Young Woman

To the Editor: Immunoglobulin G4-related disease (IgG4-RD) is a recognized systemic condition that can affect almost every organ system1. The most commonly involved organs are the pancreas, salivary glands, and biliary tree. The common presentation with central nervous system (CNS) involvement is hypophysitis and pachymeningitis, but rarely leptomeningitis2. Only 3 reported cases of leptomeningitis have been reported, all of them presenting as...