Icons / Logo / Facebook Created with Sketch. Icons / Logo / Google Created with Sketch. Icons / Logo / ORCID Created with Sketch. Branding/Logomark minus Citation Combined Shape Icon/Bookmark-empty Icon/Copy Icon/Collection Icon/Close Copy 7 no author result Created with Sketch. Icon/Back Created with Sketch. Match!

Trait conscientiousness and the personality meta-trait stability are associated with regional white matter microstructure

Published on Aug 1, 2016in Social Cognitive and Affective Neuroscience 3.66
· DOI :10.1093/scan/nsw037
Gary J. Lewis15
Estimated H-index: 15
(RHUL: Royal Holloway, University of London),
Simon R. Cox17
Estimated H-index: 17
(Edin.: University of Edinburgh)
+ 6 AuthorsIan J. Deary121
Estimated H-index: 121
(Edin.: University of Edinburgh)
Cite
Abstract
Establishing the neural bases of individual differences in personality has been an enduring topic of interest. However, while a growing literature has sought to characterize grey matter correlates of personality traits, little attention to date has been focused on regional white matter correlates of personality, especially for the personality traits agreeableness, conscientiousness and openness. To rectify this gap in knowledge we used a large sample (n > 550) of older adults who provided data on both personality (International Personality Item Pool) and white matter tract-specific fractional anisotropy (FA) from diffusion tensor MRI. Results indicated that conscientiousness was associated with greater FA in the left uncinate fasciculus (b ¼ 0.17, P < 0.001). We also examined links between FA and the personality meta-trait ‘stability’, which is defined as the common variance underlying agreeableness, conscientiousness, and neuroticism/emotional stability. We observed an association between left uncinate fasciculus FA and stability (b ¼ 0.27, P < 0.001), which fully accounted for the link between left uncinate fasciculus FA and conscientiousness. In sum, these results provide novel evidence for links between regional white matter microstructure and key traits of human personality, specifically conscientiousness and the meta-trait, stability. Future research is recommended to replicate and address the causal directions of these associations.
  • References (51)
  • Citations (6)
Cite
References51
Newest
Published on May 7, 2015
Sarah E. MacPherson19
Estimated H-index: 19
,
Sergio Della Sala50
Estimated H-index: 50
+ 2 AuthorsMatthew Iveson2
Estimated H-index: 2
1. Introduction: Fractionating the Frontal Lobe Syndrome 2. Abstraction 3. Initiation and Inhibition 4. Mental Flexibility 5. Multitasking 6. Problem Solving and Judgment 7. Working Memory 8. Emotional Processing 9. Social Decision-Making 10. Theory of Mind 11. Test Summary Tables 12. Overall Summary Table
Published on Nov 11, 2014in Frontiers in Behavioral Neuroscience 2.62
Maria Jalbrzikowski21
Estimated H-index: 21
(Semel Institute for Neuroscience and Human Behavior),
Julio E. Villalon-Reina8
Estimated H-index: 8
(SC: University of Southern California)
+ 4 AuthorsCarrie E. Bearden58
Estimated H-index: 58
(Semel Institute for Neuroscience and Human Behavior)
22q11.2 Microdeletion Syndrome (22q11DS) is a highly penetrant genetic mutation associated with a significantly increased risk for psychosis. Aberrant neurodevelopment may lead to inappropriate neural circuit formation and cerebral dysconnectivity in 22q11DS, which may contribute to symptom development. Here we examined: 1) differences between 22q11DS participants and typically developing controls in diffusion tensor imaging (DTI) measures within white matter tracts; 2) whether there is an alter...
Published on Sep 30, 2014in Neurology 8.69
Julie Staals22
Estimated H-index: 22
,
Stephen Makin11
Estimated H-index: 11
(Edin.: University of Edinburgh)
+ 2 AuthorsJoanna M. Wardlaw86
Estimated H-index: 86
(Edin.: University of Edinburgh)
Objectives: In this cross-sectional study, we tested the construct validity of a “total SVD score,” which combines individual MRI features of small-vessel disease (SVD) in one measure, by testing associations with vascular risk factors and stroke subtype. Methods: We analyzed data from patients with lacunar or nondisabling cortical stroke from 2 prospective stroke studies. Brain MRI was rated for the presence of lacunes, white matter hyperintensities, cerebral microbleeds, and perivascular space...
Published on Apr 15, 2014in Neurology 8.69
Joanna M. Wardlaw86
Estimated H-index: 86
(Edin.: University of Edinburgh),
Michael Allerhand14
Estimated H-index: 14
(Edin.: University of Edinburgh)
+ 7 AuthorsIan J. Deary121
Estimated H-index: 121
(Edin.: University of Edinburgh)
Objective: To determine the magnitude of potentially causal relationships among vascular risk factors (VRFs), large-artery atheromatous disease (LAD), and cerebral white matter hyperintensities (WMH) in 2 prospective cohorts. Methods: We assessed VRFs (history and measured variables), LAD (in carotid, coronary, and leg arteries), and WMH (on structural MRI, visual scores and volume) in: (a) community-dwelling older subjects of the Lothian Birth Cohort 1936, and (b) patients with recent nondisabl...
Published on Jan 1, 2014in Health Psychology 3.53
Tom Booth13
Estimated H-index: 13
(Edin.: University of Edinburgh),
René Mõttus15
Estimated H-index: 15
(UT: University of Tartu)
+ 12 AuthorsMaria del C. Valdés Hernández31
Estimated H-index: 31
(Edin.: University of Edinburgh)
Published on Jun 1, 2013in Psychological Medicine 5.64
Andrew M. McIntosh67
Estimated H-index: 67
(Edin.: University of Edinburgh),
Mark E. Bastin49
Estimated H-index: 49
(Edin.: University of Edinburgh)
+ 9 AuthorsJohn M. Starr83
Estimated H-index: 83
(Edin.: University of Edinburgh)
BACKGROUND: Clinical depression is associated with reductions in white-matter integrity in several long tracts of the brain. The extent to which these findings are localized or related to depressive symptoms or personality traits linked to disease risk remains unclear. Method Members of the Lothian Birth Cohort 1936 (LBC936) were assessed in two waves at mean ages of 70 and 73 years. At wave 1, they underwent assessments of depressive symptoms and the personality traits of neuroticism and extrav...
Published on Feb 1, 2013in Social Cognitive and Affective Neuroscience 3.66
Ingrid R. Olson41
Estimated H-index: 41
(Albert Einstein College of Medicine),
David McCoy3
Estimated H-index: 3
(Albert Einstein College of Medicine)
+ 1 AuthorsLars A. Ross13
Estimated H-index: 13
(Albert Einstein College of Medicine)
Memory for people and their relationships, along with memory for social language and social behaviors, constitutes a specific type of semantic memory termed social knowledge. This review focuses on how and where social knowledge is represented in the brain. We propose that portions of the anterior temporal lobe (ATL) play a critical role in representing and retrieving social knowledge. This includes memory about people, their names and biographies and more abstract forms of social memory such as...
Published on Jan 1, 2013
Michael D. Robinson50
Estimated H-index: 50
,
Edward R. Watkins2
Estimated H-index: 2
,
Eddie Harmon-Jones63
Estimated H-index: 63
Part I: Overview of This Volume. Robinson, Watkins, Harmon-Jones, Cognition and Emotion: An Introduction. Part II: Biological Factors and Considerations. Nikolova, Bogdan, R. Hariri, Neurogenetics Approaches: Insights from Studies of Dopamine Signaling and Reward Processing. Weinberg, Ferri, Hajcak, Interactions between Attention and Emotion: Insights from the Late Positive Potential. Pessoa, Pereira, Cognition-Emotion Interactions: A Review of the Functional Magnetic Resonance Imaging Literatur...
Published on Jan 1, 2013in NeuroImage 5.81
Astrid Bjørnebekk8
Estimated H-index: 8
(University of Oslo),
Anders M. Fjell55
Estimated H-index: 55
(University of Oslo)
+ 3 AuthorsLars T. Westlye46
Estimated H-index: 46
(University of Oslo)
article i nfo Article history: Accepted 3 October 2012 Available online 12 October 2012 Advancesin neuroimaging techniqueshave recently provided glimpse intothe neurobiology of complex traits of human personality. Whereas some intriguing findings have connected aspects of personality to variations in brain morphology, the relations are complex and our current understanding is incomplete. Therefore, we aimedtoprovideacomprehensiveinvestigationofbrain-personalityrelationsusingamultimodalneuroimagi...
Cited By6
Newest
Published on Apr 3, 2019in Psychophysiology 3.38
Lauren Delaparte4
Estimated H-index: 4
(SBU: Stony Brook University),
Elizabeth Bartlett2
Estimated H-index: 2
(SBU: Stony Brook University)
+ 5 AuthorsRoman Kotov36
Estimated H-index: 36
(SBU: Stony Brook University)
Published on Apr 1, 2019in NMR in Biomedicine 3.41
Yaniv Assaf43
Estimated H-index: 43
(TAU: Tel Aviv University),
Heidi Johansen-Berg80
Estimated H-index: 80
(John Radcliffe Hospital),
M Thiebaut de Schotten1
Estimated H-index: 1
(University of Paris)
Diffusion-weighted imaging has pushed the boundaries of neuroscience by allowing us to examine the white matter microstructure of the living human brain. By doing so, it has provided answers to fundamental neuroscientific questions, launching a new field of research that had been largely inaccessible. We briefly summarize key questions that have historically been raised in neuroscience concerning the brain's white matter. We then expand on the benefits of diffusion-weighted imaging and its contr...
Published on Jan 8, 2019in Frontiers in Psychology 2.13
Cristelle Rodriguez10
Estimated H-index: 10
,
Akshay Kumar Jagadish + 4 AuthorsPanteleimon Giannakopoulos55
Estimated H-index: 55
The revised NEO Personality Inventory (NEOPI-R), popularly known as the five-factor model, defines five personality factors: Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientiousness. The structural correlates of these personality factors are still a matter of debate. In this work, we examine the impact of subtle cognitive deficits on structural substrates of personality in the elderly using DTI derived white matter (WM) integrity measure, Fractional Anisotropy (FA)...
Published on Aug 1, 2018in NeuroImage 5.81
Gary J. Lewis15
Estimated H-index: 15
(RHUL: Royal Holloway, University of London),
David Alexander Dickie1
Estimated H-index: 1
(Western General Hospital)
+ 6 AuthorsIan J. Deary121
Estimated H-index: 121
(Edin.: University of Edinburgh)
Abstract The neural correlates of human personality have been of longstanding interest; however, most studies in the field have relied on modest sample sizes and few replicable results have been reported to date. We investigated relationships between personality and brain gray matter in a sample of generally healthy, older (mean age 73 years) adults from Scotland drawn from the Lothian Birth Cohort 1936. Participants (N = 578) completed a brain MRI scan and self-reported Big Five personality tra...
Published on May 1, 2018in Child Development 5.02
Lia Ferschmann3
Estimated H-index: 3
(University of Oslo),
Anders M. Fjell55
Estimated H-index: 55
(University of Oslo)
+ 3 AuthorsChristian K. Tamnes31
Estimated H-index: 31
(University of Oslo)
How personality traits relate to structural brain changes in development is an important but understudied question. In this study, cortical thickness (CT) and surface area (SA), estimated using magnetic resonance imaging (MRI), were investigated in 99 participants aged 8-19 years. Follow-up MRI data were collected after on average 2.6 years for 74 individuals. The Big Five personality traits were related to longitudinal regional CT or SA development, but limited cross-sectional relations were ob...
Published on Apr 1, 2019in NMR in Biomedicine 3.41
Yaniv Assaf43
Estimated H-index: 43
(TAU: Tel Aviv University),
Heidi Johansen-Berg80
Estimated H-index: 80
(John Radcliffe Hospital),
Michel Thiebaut de Schotten33
Estimated H-index: 33
(University of Paris)
Diffusion-weighted imaging has pushed the boundaries of neuroscience by allowing us to examine the white matter microstructure of the living human brain. By doing so, it has provided answers to fundamental neuroscientific questions, launching a new field of research that had been largely inaccessible. We briefly summarize key questions that have historically been raised in neuroscience concerning the brain's white matter. We then expand on the benefits of diffusion-weighted imaging and its contr...
Published on Jan 24, 2017in Social Cognitive and Affective Neuroscience 3.66
Roberta Riccelli8
Estimated H-index: 8
,
Nicola Toschi25
Estimated H-index: 25
(Harvard University)
+ 2 AuthorsLuca Passamonti26
Estimated H-index: 26
(University of Cambridge)
R.R. was funded by the University ‘Magna Graecia’ of Catanzaro, while L.P. was funded by the Italian National Research Council and the University of Cambridge. AT was funded by the National Institute on Aging (NIA), National Institutes of Health (NIH; 1R03AG051960-01) and by the Florida Department of Health ‘Ed and Ethel Moore Alzheimer’s Disease Research Program’ (6AZ09). Data were provided by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil U...