Cyproterone acetate vs leuprolide acetate in combination with transdermal oestradiol in transwomen: a comparison of safety and effectiveness

Summary Objective To retrospectively compare the effectiveness and safety of 1‐year administration of transdermal oestradiol ( TE ) with cyproterone acetate ( CPA ) or leuprolide acetate (Leu) in transwomen. Design, patients and measurements Forty transwomen received 50 mg of CPA daily orally ( n = 20; CPA +E group) or Leu at a dose of 3·75 mg i.m. monthly ( n = 20; Leu+E group) in combination with TE at a dose of 1 or 2 mg daily for 1 year....