Development of integrated high-resolution three-dimensional MRI and computational modelling techniques to identify novel genetic and anthropometric determinants of cardiac form and function

BackgroundThe genetic and environmental factors that define cardiac structure and function, particularly at the intersection between health and the earliest stages of disease, remain poorly characterised. Conventional cardiovascular imaging provides limited, semi-quantitative, and global metrics of the heart, and these methods are insensitive to regional variation. We aimed to assess whether three-dimensional (3D) cardiac magnetic resonance...