Original paper

Protein Crystallization in an Actuated Microfluidic Nanowell Device

Volume: 16, Issue: 4, Pages: 2074 - 2082
Published: Mar 18, 2016
Abstract
Protein crystallization is a major bottleneck of structure determination by X-ray crystallography, hampering the process by years in some cases. Numerous matrix screening trials using significant amounts of protein are often applied, while a systematic approach with phase diagram determination is prohibited for many proteins that can only be expressed in small amounts. Here, we demonstrate a microfluidic nanowell device implementing protein...
Paper Details
Title
Protein Crystallization in an Actuated Microfluidic Nanowell Device
Published Date
Mar 18, 2016
Volume
16
Issue
4
Pages
2074 - 2082
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