Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer

Obesity, insulin resistance, and elevated levels of circulating proinflammatory mediators are associated with poorer prognosis in early-stage breast cancer. To investigate whether white adipose tissue (WAT) inflammation represents a potential unifying mechanism, we examined the relationship between breast WAT inflammation and the metabolic syndrome and its prognostic importance.WAT inflammation was defined by the presence of dead/dying...