Review paper
Regulation of metabolism by the innate immune system
Abstract
Low-grade tissue inflammation induced by obesity can result in insulin resistance, which in turn is a key cause of type 2 diabetes mellitus. Cells of the innate immune system produce cytokines and other factors that impair insulin signalling, which contributes to the connection between obesity and the onset of type 2 diabetes mellitus. Here, we review the innate immune cells involved in secreting inflammatory factors in the obese state. In the...
Paper Details
Title
Regulation of metabolism by the innate immune system
Published Date
Nov 10, 2015
Journal
Volume
12
Issue
1
Pages
15 - 28
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