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Nature Reviews Endocrinology
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24.65
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2647
Papers 2669
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#1Gopika G. Nair (UCSF: University of California, San Francisco)H-Index: 5
#2Emmanuel S. Tzanakakis (Tufts University)H-Index: 18
Last. Matthias Hebrok (UCSF: University of California, San Francisco)H-Index: 57
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Diabetes mellitus, which affects more than 463 million people globally, is caused by the autoimmune ablation or functional loss of insulin-producing β-cells, and prevalence is projected to continue rising over the next decades. Generating β-cells to mitigate the aberrant glucose homeostasis manifested in the disease has remained elusive. Substantial advances have been made in producing mature β-cells from human pluripotent stem cells that respond appropriately to dynamic changes in glucose conce...
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#1Nicola Napoli (WashU: Washington University in St. Louis)H-Index: 33
#2Ann L. Elderkin (American Society for Bone and Mineral Research)H-Index: 2
Last. Sundeep Khosla (Mayo Clinic)H-Index: 104
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The COVID-19 pandemic has broad implications for the care of patients with bone fragility. A dramatic surge in fractures and related mortality is expected in the next few months. We pledge to intensify the current efforts to improve the management of bone health, and to prioritize fragility fracture care and prevention.
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#1Roya Kelishadi (IUMS: Isfahan University of Medical Sciences)H-Index: 56
Available interventions for adolescents with obesity are based on behavioural therapy and lifestyle modification. A new randomized, controlled trial provides evidence of efficacy of a pharmacological therapy, liraglutide, for weight control in adolescent obesity. The indications for more widespread use of this medication in clinical practice are under discussion.
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#1Lawrence Kazak (McGill University)H-Index: 22
#2Paul Cohen (Rockefeller University)H-Index: 40
Perturbations in metabolic processes are associated with diseases such as obesity, type 2 diabetes mellitus, certain infections and some cancers. A resurgence of interest in creatine biology is developing, with new insights into a diverse set of regulatory functions for creatine. This resurgence is primarily driven by technological advances in genetic engineering and metabolism as well as by the realization that this metabolite has key roles in cells beyond the muscle and brain. Herein, we highl...
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Top fields of study
Endocrinology
Type 2 Diabetes Mellitus
Obesity
Diabetes mellitus
Medicine