Chemistry

Antimicrobial

Biology

Geraniol

Linalool

Microbiology

Glycoside

Essential oil

Genetics

Botany

Bioassay

Nepeta

Citronellol

Traditional medicine

Medicine

The essential oil of the aerial parts of Nepeta septemcrenata Erenb was analyzed by GC/MS. Thirty nine compounds, accounting for 98.3% of the total oil, were identified, where the main constituents were 4aα, 7α, 7aβ-nepetalactone (24.2%), 4aα, 7α, 7aα-nepetalactone (19.9%), elemol (13.8%), 1, 8-cineole (8.5%), linalool (5.6%), β -bisbolene (3.7%), Terpine-4-ol (2.7%) and α-terpinol (2.5%). The antimicrobial activity of the essential oil of N. septemcrenata was tested against six gram-negative or gram-positive bacteria and six fungi, where the results of the bioassays showed interesting antimicrobial activity, in which Bacillus subtilis, Staphylococcus aureus and Escherichia coli were the most sensitive to the oil. Meanwhile the oil exhibited a remarkable antifungal activity against all the tested fungi. The iridoid glycosides (ajugol, ajugoside and aucubin) were separated and identified from the plant.

Essential oil and iridoide glycosides of Nepeta septemcrenata Erenb