Mannose-binding lectin polymorphisms and rheumatoid arthritis: A short review and meta-analysis
Abstract
Mannose-binding lectin (MBL) is a pattern recognition receptor of the lectin pathway of complement system. MBL binds to carbohydrates on microorganism’s surfaces leading to complement activation, opsonization and phagocytosis. Polymorphisms in the MBL gene (MBL2) are associated with variations on MBL serum levels and with the susceptibility to various infectious and autoimmune diseases. The involvement of the lectin pathway in rheumatoid...
Paper Details
Title
Mannose-binding lectin polymorphisms and rheumatoid arthritis: A short review and meta-analysis
Published Date
Jan 1, 2016
Journal
Volume
69
Pages
77 - 85
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