TWO-LEVEL RESAMPLING AS A NOVEL METHOD FOR THE CALCULATION OF THE EXPECTED VALUE OF SAMPLE INFORMATION IN ECONOMIC TRIALS

It has already been pointed out that the bootstrap can be used to calculate the expected value of perfect information (EVPI) when individual‐level data from a randomized controlled trial (RCT) is at hand. However, as mentioned by others, it is not clear if and how such a method can be extended to calculate the expected value of sample information (EVSI). In this article, we provide a nonparametric definition for EVPI and EVSI, which is based on...