Inhibition of Fibrinolysis by Lipoprotein(a)

A bstract : A high plasma concentration of lipoprotein Lp(a) is now considered to be a major and independent risk factor for cerebro‐ and cardiovascular atherothrombosis. The mechanism by which Lp(a) may favour this pathological state may be related to its particular structure, a plasminogen‐like glycoprotein, apo(a), that is disulfide linked to the apo B100 of an atherogenic LDL‐like particle. Apo(a) exists in several isoforms defined by a...