Original paper
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes
Abstract
In this study, we investigated the effects of interleukin-1β (IL-1β), a typical proinflammatory cytokine on the β-adrenoreceptor-stimulated induction of uncoupling protein 1 (UCP1) expression in adipocytes. IL-1β mRNA expression levels were upregulated in white adipose tissues of obese mice and in RAW264.7 macrophages under conditions designed to mimic obese adipose tissue. Isoproterenol-stimulated induction of UCP1 mRNA expression was...
Paper Details
Title
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes
Published Date
Jan 1, 2016
Journal
Volume
77
Pages
107 - 114
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Notes
History