Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle
Abstract
Dietary intake of long-chain fatty acids (LCFAs) plays a causative role in insulin resistance and risk of diabetes. Whereas LCFAs promote lipid accumulation and insulin resistance, diets rich in medium-chain fatty acids (MCFAs) have been associated with increased oxidative metabolism and reduced adiposity, with few deleterious effects on insulin action. The molecular mechanisms underlying these differences between dietary fat subtypes are poorly...
Paper Details
Title
Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle
Published Date
Dec 1, 2013
Journal
Volume
54
Issue
12
Pages
3322 - 3333
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